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Atheroprotective Reverse Cholesterol Transport Pathway Is Defective in Familial Hypercholesterolemia

Archive ouverte | Bellanger, Natacha | CCSD

International audience. Objective— Low high-density lipoprotein (HDL) cholesterol levels are frequently observed in familial hypercholesterolemia (FH) and might be associated with functional alterations of HDL parti...

Postprandial lipemia enhances the capacity of large HDL2 particles to mediate free cholesterol efflux via SR-BI and ABCG1 pathways in type IIB hyperlipidemia.

Archive ouverte | Julia, Zélie | CCSD

International audience. Lipid and cholesterol metabolism in the postprandial phase is associated with both quantitative and qualitative remodeling of HDL particle subspecies that may influence their anti-atherogenic...

Elevated CETP Activity Improves Plasma Cholesterol Efflux Capacity From Human Macrophages in Women

Archive ouverte | Villard, Elise | CCSD

International audience. Objective— We aim to identify the impact of endogenous cholesteryl ester transfer protein (CETP) activity on plasma capacity to mediate free cholesterol efflux from human macrophages. Methods...

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