In-vivo and in-vitro impact of high-dose rate radiotherapy using flattening-filter-free beams on the anti-tumor immune response

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Laurent, P.A. | Kownacka, A. | Boidot, Romain | Richard, C. | Limagne, E. | Morgand, V. | Froidurot, L. | Bonin, C. | Aubignac, L. | Ghiringhelli, F. | Créhange, G. | Mirjolet, C.

Edité par CCSD ; Elsevier -

International audience. Highlights • Effect of RT dose rate modulation on immune response has never been evaluated. • Preclinical study using FFF RT technique in vivo and in vitro. • RT dose rate did not influence radio-immune response parameters. • We may modulate RT dose rate in association with immunotherapy without efficacy modification.

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