Probing Tumour Proteostasis and the UPR with Serum Markers

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Galmiche, Antoine | Sauzay, Chloé | Houessinon, Aline | Chauffert, Bruno | Pluquet, Olivier

Edité par CCSD ; Cell Press -

International audience. Tumour proteostasis and the unfolded protein response (UPR) are emerging drivers of tumour progression and important determinants of clinical efficacy of cancer therapy. Recent findings indicate that they also regulate the production of protein tumour markers. Here, we discuss how this new knowledge opens up new perspectives for cancer therapeutics.

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