A role for membrane IgD in the tolerance of pathological human rheumatoid factor B cells

Archive ouverte | Soulas, Pauline | CCSD

Under non-autoimmune conditions, rheumatoid factor (RF) B cells coexist peacefully with their antigen (IgG), or can be transiently activated during secondary immune responses because they can present xenoantigens to specific T cel...

B Cell Positive Selection by Soluble Self-Antigen

Archive ouverte | Julien, Sylvie | CCSD

B Cell Signature during Inactive Systemic Lupus Is Heterogeneous: Toward a Biological Dissection of Lupus.

Archive ouverte | Garaud, Jean-Claude | CCSD

International audience. Systemic lupus erythematosous (SLE) is an autoimmune disease with an important clinical and biological heterogeneity. B lymphocytes appear central to the development of SLE which is character...