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The splicing factor SR45 affects the RNA-directed DNA methylation pathway in Arabidopsis

Archive ouverte | Ausin, Israel | CCSD

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Dynamic enhancer partitioning instructs activation of a growth regulator during exit from naïve pluripotency

Archive ouverte | Greenberg, Maxim V.C. | CCSD

SUMMARY During early mammalian development, the genome undergoes profound transitions in chromatin states, topological organization and recruitment of cis regulatory factors involved in transcriptional control. How these three lay...

The embryonic DNA methylation program modulates the cis- regulatory landscape via CTCF antagonism

Archive ouverte | Monteagudo-Sánchez, Ana | CCSD

Abstract During mammalian embryogenesis, both the 5-cytosine DNA methylation (5meC) landscape and three-dimensional (3D) chromatin architecture are profoundly remodeled during a process known as “epigenetic reprogramming.” An unde...

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