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RNase1 prevents the damaging interplay between extracellular RNA and tumour necrosis factor-α in cardiac ischaemia/reperfusion injury

Archive ouverte | Cabrera-Fuentes, Hector | CCSD

International audience. Summary Despite optimal therapy, the morbidity and mortality of patients presenting with an acute myocardial infarction (MI) remain significant, and the initial mechanistic trigger of myocard...

The Staphylococcus aureus Extracellular Adherence Protein Eap Is a DNA Binding Protein Capable of Blocking Neutrophil Extracellular Trap Formation

Archive ouverte | Eisenbeis, Janina | CCSD

International audience

Altered fibrin clot structure contributes to thrombosis risk in severe COVID-19

Archive ouverte | Wygrecka, Malgorzata | CCSD

Abstract The high incidence of thrombotic events suggests a possible role of the contact system pathway in COVID-19 pathology. Here, we demonstrate altered levels of factor XII (FXII) and its activation products in two independent...

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