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Microfibrils and fibrillin-1 induce integrin-mediated signaling, proliferation and migration in human endothelial cells.

Archive ouverte | Mariko, Boubacar | CCSD

International audience. Microfibrils are macromolecular complexes associated with elastin to form elastic fibers that endow extensible tissues, such as arteries, lungs, and skin, with elasticity property. Fibrillin-...

Role of fibrillin-1 in the cardiovascular function during ageing : fibrillin-1 signalling in human endothelial cells and structural and functional exploration in Fbn-1+/mg delta mice.. Rôle de la fibrilline-1 dans la fonction cardiovasculaire au cours du vieillissement : signalisation de la fibrilline-1 dans les cellules endothéliales humaines et exploration structurale et fonctionnelle chez les souris Fbn-1+/mgΔ.

Archive ouverte | Mariko, Boubacar | CCSD

Fibrillin-1, the main component of microfibrils and second main component of elastic fibers, is a glycoprotein whose gene mutation in human is responsible for Marfan syndrome, characterized at the vascular level by aortic aneurysm...

Platelet and Erythrocyte Sources of S1P Are Redundant for Vascular Development and Homeostasis, but Both Rendered Essential After Plasma S1P Depletion in Anaphylactic Shock

Archive ouverte | Gazit, Salomé, L | CCSD

International audience. RATIONALE:Sphingosine-1-phosphate (S1P) signaling is essential for vascular development and postnatal vascular homeostasis. The relative importance of S1P sources sustaining these processes r...

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