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Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma.

Archive ouverte | Zhang, Zhikun | CCSD

International audience. Atopic dermatitis (AD) is often the initial step in the "atopic march," given that more than half of AD patients with moderate to severe AD develop asthma later in life. Both AD and asthma sh...

Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis.

Archive ouverte | Li, Mei | CCSD

International audience. We have demonstrated that cytokine thymic stromal lymphopoietin (TSLP), whose expression is rapidly induced upon keratinocyte-selective ablation of retinoid X receptors (RXRs) -alpha and -bet...

Induction of thymic stromal lymphopoietin expression in keratinocytes is necessary for generating an atopic dermatitis upon application of the active vitamin D3 analogue MC903 on mouse skin.

Archive ouverte | Li, Mei | CCSD

International audience

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