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The Human T-Lymphotropic Virus Type 1 Tax Protein Inhibits Nonsense-Mediated mRNA Decay by Interacting with INT6/EIF3E and UPF1

Archive ouverte | Mocquet, Vincent | CCSD

International audience. ABSTRACT In this report, we analyzed whether the degradation of mRNAs by the nonsense-mediated mRNA decay (NMD) pathway was affected in human T-lymphotropic virus type 1 (HTLV-1)-infected cel...

The Andes hantavirus NSs protein is expressed from the viral small mRNA by a leaky scanning mechanism.

Archive ouverte | Vera-Otarola, Jorge | CCSD

International audience. The small mRNA (SmRNA) of all Bunyaviridae encodes the nucleocapsid (N) protein. In 4 out of 5 genera in the Bunyaviridae, the smRNA encodes an additional nonstructural protein denominated NS...

miRNA repression of translation in vitro takes place during 43S ribosomal scanning.

Archive ouverte | Ricci, Emiliano P | CCSD

International audience. microRNAs (miRNAs) regulate gene expression at multiple levels by repressing translation, stimulating deadenylation and inducing the premature decay of target messenger RNAs (mRNAs). Although...

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