To vaccinate or not: Influenza virus and lung cancer progression

Archive ouverte

Angrini, Mahmud | Varthaman, Aditi | Garcia-Verdugo, Ignacio | Sallenave, Jean-Michel | Alifano, Marco | Cremer, Isabelle

Edité par CCSD ; Cell Press -

International audience. Influenza virus infection leads to severe and complicated disease, particularly in patients with lung cancer. It alters the tumor microenvironment (TME), which may potentiate lung cancer progression and disrupt responses to antitumoral treatments. Consequently, influenza vaccination and antiviral treatments should be recommended to all patients with lung cancer.

Suggestions

Du même auteur

Acute influenza infection promotes lung tumor growth by reprogramming the tumor microenvironment. L'infection aiguë par le virus de la grippe favorise la croissance des tumeurs pulmonaires en reprogrammant le microenvironnement tumoral

Archive ouverte | Garmendia, Irati | CCSD

International audience

Natural killer cells in the human lung tumor microenvironment display immune inhibitory functions

Archive ouverte | Russick, Jules | CCSD

International audience. Background: Natural killer (NK) cells play a crucial role in tumor immunosurveillance through their cytotoxic effector functions and their capacity to interact with other immune cells to buil...

Influenza A induces the major secreted airway mucin MUC5AC in a protease–EGFR–extracellular regulated kinase–Sp1–dependent pathway

Archive ouverte | Barbier, Diane | CCSD

International audience. Mucins, the main glycoproteins present within mucus, modulate the rheologic properties of airways and participate in lung defense. They are thought to be able to trap and eliminate microorgan...

Chargement des enrichissements...