A structure-function study of ZraP and ZraS provides new insights into the two-component system Zra

Archive ouverte

Taher, Raleb | de Rosny, Eve

Edité par CCSD ; Elsevier -

International audience. Zra belongs to the envelope stress response (ESR) two-component systems (TCS). It is atypical because of its third periplasmic repressor partner (ZraP), in addition to its histidine kinase sensor protein (ZraS) and its response regulator (ZraR) components. Furthermore, although it is activated by Zn2+, it is not involved in zinc homeostasis or protection against zinc toxicity. Here, we mainly focus on ZraS but also provide information on ZraP.

Suggestions

Du même auteur

The Two-Component System ZraPSR Is a Novel ESR that Contributes to Intrinsic Antibiotic Tolerance in Escherichia coli

Archive ouverte | Rome, Kevin | CCSD

International audience. During their lifecycle, bacteria are exposed to continuous changes in their environment, some of which are stressful and can be harmful. The cell envelope is the first line of defense against...

Targeting the phosphatidylglycerol lipid: An amphiphilic dendrimer as a promising antibacterial candidate

Archive ouverte | Zhang, Nian | CCSD

International audience. The rapid emergence and spread of multidrug-resistant bacterial pathogens require the development of antibacterial agents that are robustly effective while inducing no toxicity or resistance ...

Study of the activation of Zra system : regulation of ZraS zinc activation by the accessory protein of the systeme ZraP. Etude de l'activation du système Zra : régulation de l'activation de ZraS par ZraP la protéine accessoire du système

Archive ouverte | Taher, Raleb | CCSD

Bacteria are exposed to external perturbations due to environmental changes or to the presence of noxious agents. Because the bacterial cell envelope forms the barrier between the inside and the outside of the cell it is highly su...

Chargement des enrichissements...