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First report of knockdown mutations in the malaria vector Anopheles gambiae from Cameroon.

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Etang, Josiane | Fondjo, Etienne | Chandre, Fabrice | Morlais, Isabelle | Brengues, Cecile | Nwane, Philippe | Chouaibou, Mouhamadou | Ndjemai, Hamadou | Simard, Frédéric

Edité par CCSD ; American Society of Tropical Medicine and Hygiene -

International audience. We report the first finding of the knockdown Leu-Phe and Leu-Ser mutations associated with resistance to pyrethroids and DDT insecticides in the malaria mosquito Anopheles gambiae from Cameroon. The Leu-Phe mutation was found in both the M and S molecular forms of An. gambiae. Importantly, two specimens of the S molecular form were found to carry both mutations in a heterozygous state.

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