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First attempt to validate the gSG6-P1 salivary peptide as an immuno-epidemiological tool for evaluating human exposure to Anopheles funestus bites

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Poinsignon, Anne | Samb, Badara | Doucoure, Souleymane | Drame, Papa-Makhtar | Sarr, Jean Biram | Sow, Cheikh | Cornélie, Sylvie | Maiga, Sophie | Thiam, Cheikh | Rogerie, François | Guindo, Sohidou | Hermann, Emmanuel | Simondon, François | Dia, Ibrahima | Riveau, Gilles | Konate, Lassana | Remoue, Franck

Edité par CCSD ; John Wiley & Sons Ltd -

International audience. The development of a biomarker of exposure based on the evaluation of the human antibody response specific to Anopheles salivary proteins seems promising in improving malaria control. The IgG response specific to the gSG6-P1 peptide has already been validated as a biomarker of An. gambiae exposure. This study represents a first attempt to validate the gSG6-P1 peptide as an epidemiological tool evaluating exposure to An. funestus bites, the second main malaria vector in sub-Saharan Africa.

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