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Identification and characterization of MOSPD2, a tether protein involved in the formation of endoplasmic reticulum membrane contact sites. Identification et caractérisation de la protéine MOSPD2, un bâtisseur de sites de contact membranaire impliquant le réticulum endoplasmique

Archive ouverte | Di Mattia, Thomas | CCSD

Membrane contact sites (MCS) are specific subcellular regions where two organelles are physically connected. Such micro-domains - molecularly defined by protein-protein and/or protein membrane interactions - are involved in organe...

Faraway, so close! Functions of Endoplasmic reticulum–Endosome contacts

Archive ouverte | Di Mattia, Thomas | CCSD

International audience. Eukaryotic cells are partitioned into functionally distinct organelles. Long considered as independent units in the cytosol, organelles are actually in constant and direct interaction with ea...

A Third Musketeer on the ER: MOSPD2 is a Novel VAP-related Receptor for FFAT Motifs

Archive ouverte | Di Mattia, Thomas | CCSD

International audience. Interorganelle membrane contact sites are subcellular structures that favor exchange and communication inside the cell. Such microdomains are built by molecular bridges that create a physical...

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