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Genetic inactivation of acetylcholinesterase causes functional and structural impairment of mouse soleus muscles

Archive ouverte | Vignaud, Audrey | CCSD

International audience. Acetylcholinesterase (AChE) plays an essential role in neuromuscular transmission. Not surprisingly, neuromuscular transmission during repetitive nerve stimulation is severely depressed in th...

Genetic ablation of acetylcholinesterase alters muscle function in mice

Archive ouverte | Vignaud, Audrey | CCSD

International audience. Although acetylcholinesterase (AChE) knockout mice survive, they have abnormal neuromuscular function. We analysed further the effects of the mutation on hind limb muscle contractile properti...

Outcome of acetylcholinesterase deficiency for neuromuscular functioning

Archive ouverte | Mouisel, E. | CCSD

Acetylcholinesterase (AChE) plays an essential role in neuromuscular transmission, therefore it is surprising that AChE knockout (KO) mice could live to the adulthood. Neuromuscular functioning in KO and normal (wild type, WT) mic...

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