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Modifying the substrate specificity of Mycobacterium tuberculosis enzymes

Archive ouverte | Dedieu, Luc | CCSD

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Identification of Residues Involved in Substrate Specificity and Cytotoxicity of Two Closely Related Cutinases from Mycobacterium tuberculosis

Archive ouverte | Dedieu, Luc | CCSD

International audience. The enzymes belonging to the cutinase family are serine enzymes active on a large panel of substrates such as cutin, triacylglycerols, and phospholipids. In the M. tuberculosis H37Rv genome, ...

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Archive ouverte | Schué, Mathieu | CCSD

International audience. Cutinases are extracellular enzymes that are able to degrade cutin, a polyester protecting plant leaves and many kinds of lipids. Although cutinases are mainly found in phytopathogenic fungi ...

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