0 avis
Choroidal thickness in glaucoma patients and glaucoma suspects measured by spectral domain optical coherence tomography
Archive ouverte
Edité par CCSD ; Blackwell Publishing -
National audience. Purpose: The aim of our study was to evaluate and compare retro‐foveolar choroidal thickness (RFCT) of healthy subjects, individuals with intraocular hypertension, patients with primary open‐angle glaucoma (POAG), patients with normal tension glaucoma (NTG) and patients with primary angle‐closure glaucoma (PACG) by spectral domain optical coherence tomography (SD‐OCT). Methods: Sixty‐five healthy eyes, 30 eyes with intraocular hypertension, 90 eyes with POAG, 30 eyes with NTG and 20 eyes with PACG were included in this cross‐sectional study. RFCT, foveolar retinal thickness and average retinal nerve fiber layer thickness (RNFL) were measured by SD‐OCT (Spectralis HRA‐OCT, Heidelberg Engineering). Choroidal area was measured centered on the fovea, extending 2500 μm in temporal and nasal directions with Image J software. Parapapillary atrophy (PPA) was noted with optic nerve digital stereophotography. Humphrey 24‐2 visual field was also performed and spherical equivalent (SE) was measured with an automatic refractometer. Results: In univariate analysis, significant correlations were observed between RFCT and age, choroidal area, PPA (p<0.001), SE, intraocular pressure, topical prostaglandin analogs (p<0.030), POAG, PACG (p<0.001) and NTG (p=0.006). In multivariate analysis, RFCT was correlated with age, choroidal area, PPA and PACG (p<0.001). Average RFCT was statistically thicker in PACG patients compared to healthy subjects (341 ± 95 μm versus 235 ± 56 μm, p<0.001). Conclusion: This preliminary study showed that RFCT measured by SD‐OCT was significantly thicker in PACG compared to healthy subjects.
Consulter en ligne
Suggestions
Du même auteur
