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In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures

Archive ouverte | Rahmoun, Massilva | CCSD

Victorian Government's Operational Infrastructure Support Program Australian Postgraduate Award. International audience. In mammalian embryonic gonads, SOX9 is required for the determination of Sertoli cells that or...

Retinoic acid signaling is dispensable for somatic development and function in the mammalian ovary

Archive ouverte | Minkina, Anna | CCSD

International audience. Retinoic acid (RA) is a potent inducer of cell differentiation and plays an essential role in sex-specific germ cell development in the mammalian gonad. RA is essential for male gametogenesis...

TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway

Archive ouverte | Rossitto, Moïra | CCSD

International audience. Gonadal sexual fate in mammals is determined during embryonic development and must be actively maintained in adulthood. In the mouse ovary, oestrogen receptors and FOXL2 protect ovarian granu...

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