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Detection of prions in the plasma of presymptomatic and symptomatic patients with variant Creutzfeldt-Jakob disease

Archive ouverte | Bougard, Daisy | CCSD

Variant Creutzfeldt-Jakob disease (vCJD) is a human prion disease resulting from the consumption of meat products contaminated by the agent causing bovine spongiform encephalopathy. Evidence supporting the presence of a population...

Plasminogen-based capture combined with amplification technology for the detection of PrP(TSE) in the pre-clinical phase of infection

Archive ouverte | Segarra, Christiane | CCSD

International audience. Background: Variant Creutzfeldt-Jakob disease (vCJD) is a neurodegenerative infectious disorder, characterized by a prominent accumulation of pathological isoforms of the prion protein (PrPTS...

A confirmatory assay for the presence of PrPtse protein in human plasma

Archive ouverte | Segarra, Christiane | CCSD

International audience. Background: Variant of Creutzfeldt-Jakob disease (vCJD), the human counterpart of BSE, is a neurodegenerative infectious disorder, characterised by the prominent accumulation of the prion pro...

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