Truncated internalin A and asymptomatic Listeria monocytogenes carriage: in vivo investigation by allelic exchange

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Olier, Maïwenn | Garmyn, Dominique, D. | Rousseaux, Sandrine | Lemaître, Jean-Paul, J.-P. | Piveteau, Pascal | Guzzo, Jean

Edité par CCSD ; American Society for Microbiology -

International audience. Allelic exchange of the region coding for the C terminus of InIA between one epidemic (with an 80-kDa InIA) and one asymptomatic (with a 47-kDa InIA) carriage Listeria monocytogenes strain confirmed the need for this region for internalin entry in vitro. Interestingly, restoration of internalin A functionality did not result in full virulence in chicken embryo assays.

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