Paramecium genome survey: a pilot project.

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Dessen, P. | Zagulski, M. | Gromadka, R. | Plattner, H. | Kissmehl, R. | Meyer, E. | Betermier, M. | Schultz, J E. | Linder, J U. | Pearlman, R E. | Kung, C. | Forney, J. | Satir, B H. | van Houten, J L. | Keller, a M. | Froissard, Marine | Sperling, Linda | Cohen, J.

Edité par CCSD ; Elsevier -

International audience. A consortium of laboratories undertook a pilot sequencing project to gain insight into the genome of Paramecium. Plasmid-end sequencing of DNA fragments from the somatic nucleus together with similarity searches identified 722 potential protein-coding genes. High gene density and uniform small intron size make random sequencing of somatic chromosomes a cost-effective strategy for gene discovery in this organism.

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