First data on pneumocystis jirovecii colonization in patients with respiratory diseases in north lebanon

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Khalife, S. | Aliouat, El Moukhtar | Aliouat-Denis, Cécile-Marie | Gantois, N. | Devos, Patrick | Mallat, H. | Dei-Cas, Eduardo | Dabboussi, F. | Hamze, Monzer | Frealle, Emilie

Edité par CCSD ; Wiley Online Library -

International audience. Pneumocystis colonization may play a role in transmission and local inflammatory response. It was explored in patients with respiratory diseases in North Lebanon. Overall prevalence reached only 5.2% (95% CI 2.13-10.47) but it was higher (17.3%) in the subpopulation of patients with chronic obstructive pulmonary disease (COPD). COPD was the only factor associated with a significantly increased risk of colonization. mtLSU genotyping revealed predominance of genotype 2, identified in five patients (71.4%), including one patient who had co-infection with genotype 3. These first data in North Lebanon confirm Pneumocystis circulation among patients with respiratory diseases and the potential for transmission to immunocompromised patients.

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