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Evidence for hypothalamic ketone bodies sensing: impact on food intake and peripheral metabolic responses in mice

Archive ouverte | Carneiro, Lionel | CCSD

Monocarboxylates have been implicated in the control of energy homeostasis. Among them, the putative role of ketone bodies produced notably during high-fat diet (HFD) has not been thoroughly explored. In this study, we aimed to de...

Hypothalamic sensing of ketone bodies after prolonged cerebral exposure leads to metabolic control dysregulation

Archive ouverte | Carneiro, Lionel | CCSD

International audience. Ketone bodies have been shown to transiently stimulate food intake and modify energy homeostasis regulatory systems following cerebral infusion for a moderate period of time (< 6 hours). As k...

CDK4 is an essential insulin effector in adipocytes

Archive ouverte | Lagarrigue, Sylviane | CCSD

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