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Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4.

Archive ouverte | Espert, Lucile | CCSD

HIV-1 envelope glycoproteins (Env), expressed at the cell surface, induce apoptosis of uninfected CD4+ T cells, contributing to the development of AIDS. Here we demonstrate that, independently of HIV replication, transfected or HI...

[Autophagy and CD4 T lymphocyte destruction by HIV-1]

Archive ouverte | Espert, Lucile | CCSD

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Autophagy and CD4+ T lymphocyte destruction by HIV-1.

Archive ouverte | Espert, Lucile | CCSD

OPEN ACCESS --- http://www.landesbioscience.com/journals/autophagy/article/espertAUTO3-1.pdf. International audience. The first step of HIV-1 infection is mediated by the binding of envelope glycoproteins (Env) to C...

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