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Live-imaging of revertant and therapeutically restored dystrophin in the DmdEGFP-mdx mouse model for Duchenne muscular dystrophy

Archive ouverte | Petkova, Mina V. | CCSD

International audience. Background: Dmdmdx, harbouring the c.2983C>T nonsense mutation in Dmd exon 23, is a mouse model for Duchenne muscular dystrophy (DMD), frequently used to test therapies aimed at dystrophin...

Myostatin is a key mediator between energy metabolism and endurance capacity of skeletal muscle

Archive ouverte | Mouisel, Etienne | CCSD

International audience. Myostatin (Mstn) participates in the regulation of skeletal muscle size and has emerged as a regulator of muscle metabolism. Here, we hypothesized that lack of myostatin profoundly depresses ...

BMP signaling regulates satellite cell-dependent postnatal muscle growth

Archive ouverte | Stantzou, Amalia | CCSD

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