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Archive ouverte | Bocca, Cinzia | CCSD

International audience. OPA1 (Optic Atrophy 1) is a multi-isoform dynamin GTPase involved in the regulation of mitochondrial fusion and organization of the cristae structure of the mitochondrial inner membrane. Path...

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Archive ouverte | Chao de La Barca, Juan Manuel | CCSD

International audience. Leber's hereditary optic neuropathy (MIM#535000), the commonest mitochondrial DNA-related disease, is caused by mutations affecting mitochondrial complex I. The clinical expression of the dis...

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Archive ouverte | Bocca, Cinzia | CCSD

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