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Archive ouverte | Laboucarié, Thomas | CCSD

International audience. Gene expression regulation is essential for cells to adapt to changes in their environment. Co-activator complexes have well-established roles in transcriptional regulation, but less is known...

The Hsp90 cochaperone TTT promotes cotranslational maturation of PIKKs prior to complex assembly

Archive ouverte | Toullec, Damien | CCSD

International audience. Phosphatidylinositol 3-kinase-related kinases (PIKKs) are a family of kinases that control fundamentalprocesses, including cell growth, DNA damage repair, and gene expression. Although their ...

SCA7 mouse models show selective stabilization of mutant ataxin-7 and similar cellular responses in different neuronal cell types

Archive ouverte | Yvert, G. | CCSD

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