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Analysis of interaction between telomeric i-motif DNA and a cyclic tetraoxazole compound

Archive ouverte | Masoud, Shadi Sedghi | CCSD

International audience. The interaction of a macrocyclic tetraoxazole compound, L2H2‐4OTD (1), with two aminoalkyl side chains and telomeric i‐motif, was investigated by means of electrophoretic mobility shift assay...

Interlocking G-Quadruplexes Using a G-Triad•G Connection: Implications for G-Wire Assembly

Archive ouverte | Singh, Abhishek | CCSD

International audience. G-quadruplexes are noncanonical structures of nucleic acids formed mainly by G-rich sequences and play crucial roles in important cellular processes. They are also increasingly used in nanote...

Differential diagnosis of vitamin D‐related hypercalcemia using serum vitamin D metabolite profiling

Archive ouverte | Kaufmann, Martin | CCSD

International audience. Genetic causes of vitamin D-related hypercalcemia are known to involve mutation of 25-hydroxyvitamin D-24-hydroxylase CYP24A1 or the sodium phosphate co-transporter SLC34A1; which result in e...

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