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Are Prophylactic and Therapeutic Target Concentrations Different? The Case of Lopinavir/ritonavir or Lamivudine Administered to Infants for the Prevention of Mother-to-Child HIV-1 Transmission during Breastfeeding

Archive ouverte | Foissac, Frantz | CCSD

International audience. The ANRS 12174 trial assessed the efficacy and tolerance of lopinavir (LPV)-ritonavir (LPV/r) prophylaxis versus those of lamivudine (3TC) prophylaxis administered to breastfed infants whose ...

A new plan for extended paediatric HIV testing is needed in Africa

Archive ouverte | Molès, Jean-Pierre | CCSD

International audience

Growth in HIV-1-exposed but uninfected infants treated with lopinavir–ritonavir versus lamivudine: a secondary analysis of the ANRS 12174 trial

Archive ouverte | Blanche, Stéphane | CCSD

International audience. BackgroundThe tolerance of antiretroviral drugs in infants must be carefully evaluated. In previous studies of children with HIV type 1 (HIV-1) less weight gain was observed in children given...

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