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The carboxyl-terminal nucleoplasmic region of MAN1 exhibits a DNA binding winged helix domain

Archive ouverte | Caputo, Sandrine | CCSD

is an integral protein of the inner nuclear membrane, which interacts with nuclear lamins and emerin, thus playing a role in nuclear organization. It also binds to chromatin-associated proteins and transcriptional regulators, incl...

Dual Expression System Suitable for High-Throughput Fluorescence-Based Screening and Production of Soluble Proteins

Archive ouverte | Braud, Sandrine | CCSD

International audience

Dual expression system suitable for high-throughput fluorescence-based screening and production of soluble proteins

Archive ouverte | Braud, Sandrine | CCSD

International audience. Many studies that aim to characterize the proteome structurally or functionally require the production of pure protein in a high-throughput format. We have developed a fast and flexible integ...

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