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Integrative system biology analyses identify sevenmicroRNAs to predict heart failure

Archive ouverte | Charrier, Henri | CCSD

International audience. Heart failure (HF) has several etiologies including myocardial infarction (MI) and left 24 ventricular remodeling (LVR), but its progression remains difficult to predict in clinical practice....

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Archive ouverte | Bouvet, Marion | CCSD

International audience. Post-translational modifications of cardiac proteins could participate to left contractile dysfunction resulting in heart failure. Using a rat model of ischemic heart failure, we showed an ac...

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Archive ouverte | Peugnet, Victoriane | CCSD

International audience. Heart failure, mostly associated with cardiac hypertrophy, is a major cause of illness and death. Oxidative stress causes accumulation of reactive oxygen species (ROS), leading to mitochondri...

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