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The packaging signal of MLV is an integrated module that mediates intracellular transport of genomic RNAs

Archive ouverte | Basyuk, E. | CCSD

International audience. Packaging of MLV genomes requires four cis-acting stem-loops. Stem-loops A and B are self-complementary and bind Gag in their dimeric form, while the C and D elements mediate loop-loop intera...

Establishment of a protein frequency library and its application in the reliable identification of specific protein interaction partners

Archive ouverte | Boulon, S. | CCSD

International audience. The reliable identification of protein interaction partners and how such interactions change in response to physiological or pathological perturbations is a key goal in most areas of cell bio...

HSP90 and its R2TP/Prefoldin-like cochaperone are involved in the cytoplasmic assembly of RNA polymerase II

Archive ouverte | Boulon, S. | CCSD

International audience. RNA polymerases are key multisubunit cellular enzymes. Microscopy studies indicated that RNA polymerase I assembles near its promoter. However, the mechanism by which RNA polymerase II is ass...

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