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Aryl Hydrocarbon Receptor-Dependent Induction of Liver Fibrosis by Dioxin

Archive ouverte | Pierre, Stéphane | CCSD

International audience. The contribution of environmental pollutants to liver fibrosis is an important and poorly explored issue. In vitro studies suggest that the environmental pollutant 2,3,7,8-tetrachlorodibenzo-...

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Archive ouverte | Ambolet-Camoit, Ariane | CCSD

International audience. TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) is an environmental pollutant which binds the aryl hydrocarbon receptor (AhR), a transcription factor that triggers variousbiological responses. In ...

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Archive ouverte | Guyot, Erwan | CCSD

International audience. It is well known that several metals, such as lead, mercury, cadmium, and vanadium, can mimic the effects of estrogens (metallo-estrogens). Nevertheless, there are only a few studies that hav...

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