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Disruption of TTDA Results in Complete Nucleotide Excision Repair Deficiency and Embryonic Lethality

Archive ouverte | Theil, Arjan, F | CCSD

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Dynamic Interaction of TTDA with TFIIH Is Stabilized by Nucleotide Excision Repair in Living Cells

Archive ouverte | Mari, Giuseppina | CCSD

International audience. Transcription/repair factor IIH (TFIIH) is essential for RNA polymerase II transcription and nucleotide excision repair (NER). This multi-subunit complex consists of ten polypeptides, includi...

Generation of DNA single-strand displacement by compromised nucleotide excision repair

Archive ouverte | Godon, Camille | CCSD

International audience. Nucleotide excision repair (NER) is a precisely coordinated process essential to avoid DNA damage-induced cellular malfunction and mutagenesis. Here, we investigate the mechanistic details an...

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