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The Npr1 Kinase Controls Biosynthetic and Endocytic Sorting of the Yeast Gap1 Permease

Archive ouverte | de Craene, Johan-Owen | CCSD

International audience. Membrane trafficking of the general amino acid per-mease (Gap1) of Saccharomyces cerevisiae is under nitrogen regulation. In cells growing on proline or urea as the sole nitrogen source, newl...

Ubiquitin Is Required for Sorting to the Vacuole of the Yeast General Amino Acid Permease, Gap1

Archive ouverte | Soetens, Oriane | CCSD

International audience. In yeast, ubiquitin plays a central role in proteolysis of a multitude of proteins and serves also as a signal for endocytosis of many plasma membrane proteins. We showed previously that ubiq...

Myotubularin MTM1 Involved in Centronuclear Myopathy and its Roles in Human and Yeast Cells

Archive ouverte | Bertazzi, Dimitri | CCSD

International audience. Mutations in the MTM1 gene, encoding the phosphoinositide phosphatase myotubularin, are responsible for the X-linked centronuclear myopathy (XLCNM) or X-linked myotubular myopathy (XLMTM). Th...

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