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BrdU incorporation in multiparameter flow cytometry: A new cell cycle assessment approach in multiple myeloma

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Requirand, Guilhem | Robert, Nicolas | Boireau, Stéphanie | Vincent, Laure | Seckinger, Anja | Bouhya, Salaheddine | Ceballos, Patrice | Cartron, Guillaume | Hose, Dirk | Klein, Bernard | Moreaux, Jérôme

Edité par CCSD ; Wiley -

International audience. Mutiple myeloma (MM) is a neoplasia characterized by the accumulation of malignant plasma cells (PC) in the bone marrow. Although proliferation markers have been studied in MM, none of the current staging systems include them. Moreover, approaches used to analyze proliferation do not separate MM cells (MMCs) from normal PC.

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