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PD-L1+ plasma cells suppress T lymphocyte responses in patients with sepsis and mouse sepsis models

Archive ouverte | Gossez, Morgane | CCSD

International audience. Sepsis, a leading cause of death in intensive care units, is associated with immune alterations that increase the patients’ risk of secondary infections and mortality, so better understanding...

Integrated clustering of multiple immune marker trajectories reveals different immunotypes in severely injured patients

Archive ouverte | Bodinier, Maxime | CCSD

International audience. Abstract Background The immune response of critically ill patients, such as those with sepsis, severe trauma, or major surgery, is heterogeneous and dynamic, but its characterization and impa...

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Archive ouverte | Venet, Fabienne | CCSD

International audience. Septic patients develop immune dysfunctions, the intensities and durations of which are associated with deleterious outcomes. LILRB2 (leukocyte immunoglobulin-like receptors subfamily B, memb...

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