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Rapidly progressive diaphragmatic weakness and injury during mechanical ventilation in humans.

Archive ouverte | Jaber, Samir | CCSD

International audience. Rationale. Diaphragmatic function is a major determinant of the ability to successfully wean patients from mechanical ventilation (MV). Paradoxically, MV itself results in a rapid loss of dia...

Adaptive Support Ventilation Prevents Ventilator-induced Diaphragmatic Dysfunction in Piglet: : an in vivo and in vitro study.

Archive ouverte | Jung, Boris | CCSD

International audience. BACKGROUND: Contrary to adaptive support ventilation (ASV), prolonged totally controlled mechanical ventilation (CMV) results in the absence of diaphragm activity and causes ventilator-induce...

Rapid Onset of Specific Diaphragm Weakness in a Healthy Murine Model of Ventilator-induced Diaphragmatic Dysfunction

Archive ouverte | Mrozek, Ségolène | CCSD

International audience. Background: Controlled mechanical ventilation is associated with ventilator-induced diaphragmatic dysfunction, which impedes weaning from mechanical ventilation. To design future clinical tri...

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