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Synergistic protective effect of cyclosporin A and rotenone against hypoxia–reoxygenation in cardiomyocytes

Archive ouverte | Teixeira, Geoffrey | CCSD

International audience

A modified calcium retention capacity assay clarifies the roles of extra- and intracellular calcium pools in mitochondrial permeability transition pore opening

Archive ouverte | Harisseh, Rania | CCSD

International audience. The abbreviations used are: SERCA, sarco/endoplasmic Ca 2ϩ ATPase; CRC, Ca 2ϩ retention capacity; AR, anoxia-reoxygenation; mPTP, mitochondria permeability transition pore; CsA, cyclosporine ...

Cyclophilin D modulates the cardiac mitochondrial target of isoflurane, sevoflurane, and desflurane

Archive ouverte | Harisseh, Rania | CCSD

Background: Volatile anesthetics are known to limit myocardial ischemia-reperfusion injuries. Mitochondria were shown to be major contributors to cardioprotection. Cyclophilin D (CypD) is one of the main regulators of mitochondria...

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