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CD206 + macrophages are relevant non-invasive imaging biomarkers and therapeutic targets in experimental lung fibrosis

Archive ouverte | Pommerolle, Lenny | CCSD

International audience. Background Interstitial lung diseases (ILDs) include a large number of diseases associated with progressive pulmonary fibrosis (PPF), including idiopathic pulmonary fibrosis (IPF). Despite th...

Pleural inhibition of the caspase-1/IL-1β pathway diminishes profibrotic lung toxicity of bleomycin

Archive ouverte | Burgy, Olivier | CCSD

IF 3.751. International audience. Background: Idiopathic and toxic pulmonary fibrosis are severe diseases starting classically in the subpleural area of the lung. It has recently been suggested that pleural mesothel...

Optimising experimental research in respiratory diseases: an ERS statement

Archive ouverte | Bonniaud, Philippe | CCSD

IF 12.242. International audience. Experimental models are critical for the understanding of lung health and disease and are indispensable for drug development. However, the pathogenetic and clinical relevance of th...

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