Multicenter comparison of the etest and EUCAST methods for antifungal susceptibility testing of Candida isolates to micafungin

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Bougnoux, M.-E. | Dannaoui, E. | Accoceberry, I. | Angoulvant, A. | Bailly, E. | Botterel, F. | Chevrier, S. | Chouaki, T. | Cornet, M. | Dalle, F. | Datry, A. | Dupuis, A. | Fekkar, A. | Gangneux, J.P. | Guitard, J. | Hennequin, C. | Le Govic, Y. | Le Pape, P. | Maubon, D. | Ranque, S. | Sautour, M. | Sendid, B. | Chandenier, J.

Edité par CCSD ; American Society for Microbiology -

International audience. In vitro susceptibility of 933 Candida isolates, from 16 French hospitals, to micafungin was determined using the Etest in each center. All isolates were then sent to a single center for determination of MICs by the EUCAST reference method. Overall essential agreement between the two tests was 98.5% at ±2 log2 dilutions and 90.2% at ±1 log2 dilutions. Categorical agreement was 98.2%. The Etest is a valuable alternative to EUCAST for the routine determination of micafungin MICs in medical mycology laboratories. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

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