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A Role for RNAi in the Selective Correction of DNA Methylation Defects

Archive ouverte | Teixeira, Felipe, Karam | CCSD

International audience. DNA methylation is essential for silencing transposable elements and some genes in higher eukaryotes, which suggests that this modification must be tightly controlled. However, accidental cha...

Dynamics and biological relevance of DNA demethylation in Arabidopsis antibacterial defense

Archive ouverte | Yu, Agnès | CCSD

DNA methylation is an epigenetic mark that silences transposable elements (TEs) and repeats. Whereas the establishment and maintenance of DNA methylation are relatively well understood, little is known about their dynamics and bio...

Highly dynamic and sex-specific expression of microRNAs during early ES cell differentiation.

Archive ouverte | Ciaudo, Constance | CCSD

International audience. Embryonic stem (ES) cells are pluripotent cells derived from the inner cell mass of the mammalian blastocyst. Cellular differentiation entails loss of pluripotency and gain of lineage-specifi...

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