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Micropilot: automation of fluorescence microscopy-based imaging for systems biology.

Archive ouverte | Conrad, Christian | CCSD

International audience. Quantitative microscopy relies on imaging of large cell numbers but is often hampered by time-consuming manual selection of specific cells. The 'Micropilot' software automatically detects cel...

Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging.

Archive ouverte | Walter, Thomas | CCSD

International audience. High-throughput time-lapse microscopy is an excellent way of studying gene function by collecting time-resolved image data of the cellular responses to gene perturbations. With the increase i...

Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assay.

Archive ouverte | Pau, Gregoire | CCSD

International audience. BACKGROUND: The combination of time-lapse imaging of live cells with high-throughput perturbation assays is a powerful tool for genetics and cell biology. The Mitocheck project employed this ...

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