Invariant NKT cells drive hepatic cytokinic microenvironment favoring efficient granuloma formation and early control of Leishmania donovani infection.

Archive ouverte | Robert-Gangneux, Florence | CCSD

International audience. The development of inflammatory granulomas around infected Kupffer cells is necessary for hepatic parasite clearance during visceral leishmaniasis. Invariant NKT (iNKT) cells are predominant ...

The IL-33/ST2 axis is associated with human visceral leishmaniasis and suppresses Th1 responses in the livers of BALB/c mice infected with Leishmania donovani.

Archive ouverte | Rostan, Octavie | CCSD

International audience. UNLABELLED: During visceral leishmaniasis, the control of hepatic parasite burden is mainly due to granuloma assembly in a microenvironment consisting of both Th1 and Th2 components. Using en...

Etude de l'expression hepatique de l'interleukline-33 au cours de la leishmaniose viscerale murine

Archive ouverte | Rostan, Octavie | CCSD