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In situ lipidomic analysis of nonalcoholic fatty liver by cluster TOF-SIMS imaging.

Archive ouverte | Debois, Delphine | CCSD

International audience. Mass spectrometry imaging has been used to map liver biopsies of several patients suffering from nonalcoholic fatty liver disease. This steatosis is characterized by an accumulation of triacy...

Atmospheric pressure photoionization study of post-translational modifications: The case of palmitoylation

Archive ouverte | Bagag, Aïcha | CCSD

International audience. In this work, atmospheric pressure photoionization was investigated for use in characterizing protein palmitoylation, which is a major post-translational modification of membrane proteins. Th...

Separation of peptides from detergents using ion mobility spectrometry

Archive ouverte | Bagag, Aïcha | CCSD

International audience. Mass spectrometry (MS) has dramatically evolved in the last two decades and has been the driving force of the spectacular expansion of proteomics during this period. However, the very poor co...

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