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Carbazolequinone induction of caspase-dependent cell death in Src-overexpressing cells.

Archive ouverte | Aouacheria, A. | CCSD

International audience. We previously reported that RSV-transformed quail neuroretina cells (QNR-ts68) were highly resistant to apoptosis provoked by serum withdrawal, and that this property was due to v-Src kinase ...

Evidence for crucial electrostatic interactions between Bcl-2 homology domains BH3 and BH4 in the anti-apoptotic Nr-13 protein.

Archive ouverte | Lalle, P. | CCSD

International audience. Nr-13 is an anti-apoptotic member of the Bcl-2 family previously shown to interact with Bax. The biological significance of this interaction was explored both in yeast and vertebrate cells an...

p60(v-src) and serum control cell shape and apoptosis via distinct pathways in quail neuroretina cells.

Archive ouverte | Aouacheria, A. | CCSD

International audience. We made use of QNR cells transformed by a thermosensitive (tsNY68) strain of the Rous sarcoma virus (RSV) to compare the effect of p60(v-src) and serum in cultured nerve cells. In this system...

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