Arginine butyrate: a therapeutic candidate for Duchenne muscular dystrophy.

Archive ouverte | Vianello, Sara | CCSD

International audience. As a strategy to treat Duchenne muscular dystrophy, we used arginine butyrate, which combines two pharmacological activities: nitric oxide pathway activation, and histone deacetylase inhibiti...

L-arginine improves dystrophic phenotype in mdx mice.

Archive ouverte | Voisin, Vincent | CCSD

The NO way to increase muscular utrophin expression?

Archive ouverte | Chaubourt, Emmanuel | CCSD

Duchenne muscular dystrophy (DMD), a severe X-linked recessive disorder that results in progressive muscle degeneration, is due to a lack of dystrophin, a membrane cytoskeletal protein. An approach to the search for a treatment is...