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Physico-Pathologic Mechanisms Involved in Neurodegeneration: Misfolded Protein-Plasma Membrane Interactions.

Archive ouverte | Shrivastava, Amulya Nidhi | CCSD

International audience. Several neurodegenerative disorders, such as Alzheimer's and Parkinson's disease, are characterized by prominent loss of synapses and neurons associated with the presence of abnormally struct...

Differential Membrane Binding and Seeding of Distinct $\alpha$-Synuclein Fibrillar Polymorphs

Archive ouverte | Shrivastava, Amulya Nidhi | CCSD

International audience. The aggregation of the protein $\alpha$-Synuclein ($\alpha$-Syn) leads to different synucleinopathies. We recently showed that structurally distinct fibrillar $\alpha$-Synuclein polymorphs tr...

β-amyloid and ATP-induced diffusional trapping of astrocyte and neuronal metabotropic glutamate type-5 receptors

Archive ouverte | Shrivastava, Amulya Nidhi | CCSD

International audience

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